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moaC moaC moaA2 moaA2 moaA1 moaA1 moaE moaE moaD moaD moeA1 moeA1 moaB1 moaB1 moeA2 moeA2 moaB2 moaB2 moeB moeB fdhD fdhD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
moaCMolybdopterin biosynthetic protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (160 aa)    
Predicted Functional Partners:
moaA2
Molybdopterin biosynthetic protein A2; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
 
 0.999
moaA1
Molybdopterin biosynthetic protein A1; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
 
 0.999
moaE
Molybdopterin converting factor, large subunit; Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD (By similarity); Belongs to the MoaE family.
 
 
 0.999
moaD
Molybdopterin converting factor, small subunit; Product name confidence: Class 2 (High similarity to functionally studied protein).
 
  
 0.999
moeA1
Molybdenum cofactor biosynthetic protein A1; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
  
 0.990
moaB1
Molybdopterin biosynthetic protein B1; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family.
 
  
 0.986
moeA2
Molybdenum cofactor biosynthesis protein A2; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
  
 0.975
moaB2
Molybdopterin biosynthetic protein B2; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family.
 
  
 0.958
moeB
Molybdopterin biosynthesis MoeB protein; Product name confidence: Class 2 (High similarity to functionally studied protein).
 
   
 0.943
fdhD
Conserved hypothetical protein; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.
 
  
 0.843
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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